STUDYING SEDATIVE ACTIVITY OF COMBINED TINCTURE OF MOTHERWORT AND ST JOHN'S-WORT

نویسندگان

چکیده

The paper presents studying sedative activity of the combined tincture motherwort and St. John's wort. wort was obtained by percolation method in a ratio 1:10. Standardization carried out with quality indicators: description, content active ingredients ethanol, relative density, dry residue. According to all indicators, met requirements State Pharmacopoeia Republic Belarus. Specific assessed barbiturates hypnotic effect prolongation (sodium thiopental), rate falling asleep animals staying lateral position relation control group which sodium thiopental injected. In studies it found that injection at dose 0,1 ml / kg increases sleep 125,63% also accelerates process 327,75% compared separate doses ml/kg. It shown ml/kg exhibits potentiated enhances administered 10 mg/kg.

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ژورنال

عنوان ژورنال: Vestnik farmacii

سال: 2021

ISSN: ['2074-9457']

DOI: https://doi.org/10.52540/2074-9457.2021.2.59